Practical Applications of Organic Chemistry: Improving Student Knowledge of GC-MS through Qualitative Analysis of Nicotine in Electronic Cigarette Vapors

Autor/inn/en	Patel, Parth H.; Conrad, Kristofer L.; Pathiranage, Anuradha L.; Hiatt, Leslie A.
Titel	Practical Applications of Organic Chemistry: Improving Student Knowledge of GC-MS through Qualitative Analysis of Nicotine in Electronic Cigarette Vapors
Quelle	In: Journal of Chemical Education, 97 (2020) 11, S.4117-4122 (6 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Hiatt, Leslie A.)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9584
Schlagwörter	Organic Chemistry; Smoking; Electronic Equipment; Science Experiments; Laboratory Experiments; Introductory Courses; Undergraduate Students; Spectroscopy; Data Collection; Data Interpretation; Science Process Skills; Problem Solving + Suchen Sie Ihr Suchwort? Organische Chemie; Rauchen; Elektronisches Gerät; Laboratory work; Laborarbeit; Einführungskurs; Spektroskopie; Data capture; Datensammlung; Data evaluation; Datenauswertung; Problemlösen
Abstract	Given student familiarity with electronic cigarettes (e-cigs), this lab uses a student-built smoke collection apparatus to collect e-cig vapors to teach students about gas chromatography-mass spectrometry (GC-MS). Students in a second semester, introductory organic chemistry course spent 1 week collecting e-cig vapors and 1 week qualitatively analyzing the data collected. In the real-world, the amount of nicotine inhaled by the consumer from an e-cig is going to depend on many variables including the vaping device used, inhalation rate, and voltage applied by the e-cig. This experiment allows students to simplify the vaping process and focus on the collection of nicotine in the e-cig vapor. Students compared the retention time of nicotine with an injection standard, quinoline, whose structural similarities provided strong discussions about the role of polarity and boiling points in chromatography. This injection standard ensured that all students would minimally be able to compare the retention time of two structurally similar compounds. Each lab group analyzed different e-cig liquids. Students improved upon their ability to interpret mass spectrometry data by predicting fragmentation patterns for both nicotine and quinoline. This lab experiment serves as a connection between lecture and lab material, while promoting student engagement and learning. The students who performed this experiment increased their knowledge of GC-MS and built foundational chemistry skills that can be applied to solve other real-world questions. (As Provided).
Anmerkungen	Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01