Modeling Mendel's Laws on Inheritance in Computational Biology and Medical Sciences

Autor/inn/en	Singh, Gurmukh; Siddiqui, Khalid; Singh, Mankiran; Singh, Satpal
Titel	Modeling Mendel's Laws on Inheritance in Computational Biology and Medical Sciences
Quelle	In: Journal of Educational Technology Systems, 39 (2011) 1, S.31-46 (16 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0047-2395
Schlagwörter	Heredity; Genetics; Biological Sciences; Medical Education; Science Instruction; Science Experiments; Educational Technology; Computer Software; Computer Assisted Instruction; College Instruction; Spreadsheets; Computer Simulation; Programming; Models; New York + Suchen Sie Ihr Suchwort? Erblichkeit; Humangenetik; Abwasserbiologie; Medizinische Ausbildung; Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Unterrichtsmedien; Computer based training; Computerunterstützter Unterricht; Hochschullehre; Spread sheet; Spredsheets; Spreadsheet; Tabellenkalkulation; Computergrafik; Computersimulation; Programmierung; Analogiemodell
Abstract	The current research article is based on a simple and practical way of employing the computational power of widely available, versatile software MS Excel 2007 to perform interactive computer simulations for undergraduate/graduate students in biology, biochemistry, biophysics, microbiology, medicine in college and university classroom setting. To accomplish this important motive, we developed the necessary computer algorithm, which used a built-in pseudo-random number generating function in MS Excel 2007, to computer model two basic Mendel's Laws of heredity for plant and animal species. We performed more than 18,000 computer simulations to investigate the behavior of dominant and recessive genes to verify two basic Mendel's Laws of heredity. Our simulation work corroborates the experimental observations of Mendel's research on inheritance in "Pisum hybrid species". When we compare our results of simulated data with that of experiments done on "Drosophila melanogaster", fruit fly extensively being used as a model organism to study genetics and development, an exceedingly good agreement between the simulated and the experimental data has been observed for the F2 generation. (Contains 4 tables and 3 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10