Literaturnachweis - Detailanzeige
| Autor/inn/en | Trofimova, Ellina; Asgharzadeh Kangachar, Shahla; Weynberg, Karen D.; Willows, Robert D.; Jaschke, Paul R. |
|---|---|
| Titel | A Bacterial Genome Assembly and Annotation Laboratory Using a Virtual Machine |
| Quelle | In: Biochemistry and Molecular Biology Education, 51 (2023) 3, S.276-285 (10 Seiten)Infoseite zur Zeitschrift
PDF als Volltext |
| Zusatzinformation | ORCID (Jaschke, Paul R.) |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 1470-8175 |
| DOI | 10.1002/bmb.21720 |
| Schlagwörter | Genetics; Science Instruction; Microbiology; Information Science; Workshops; Computer Simulation; Information Systems; Computer Science Education; Computer Software; College Students; Pathology; Scientific Research |
| Abstract | With the global increase of infections caused by antibiotic-resistant bacterial strains, there is an urgent need for new methods of tackling the issue. Genomic analysis of bacterial strains can help to understand their virulence and antibiotic resistance profile. Bioinformatic skills are in great demand across the biological sciences. We designed a workshop that allows university students to learn the process of genome assembly using command-line tools within a virtual machine on a Linux operating system. We use Illumina and Nanopore short and long-read raw sequences to reveal the advantages and disadvantages of short, long, and hybrid assembly methods. The workshop teaches how to assess read and assembly quality, perform genome annotation, and analyze pathogenicity, antibiotic and phage resistance. The workshop is intended for a five-week teaching period and is concluded by a student poster presentation assessment. (As Provided). |
| Anmerkungen | Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2024/1/01 |
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