LacOp: A Free Web-Based Lac Operon Simulation That Enhances Student Learning of Gene Regulation Concepts

Autor/inn/en	Charczenko, Richard; McMahon, Madeline; Kandl, Kimberly; Rutherford, Robert
Titel	LacOp: A Free Web-Based Lac Operon Simulation That Enhances Student Learning of Gene Regulation Concepts
Quelle	In: Biochemistry and Molecular Biology Education, 50 (2022) 4, S.360-368 (9 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Rutherford, Robert)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1470-8175
DOI	10.1002/bmb.21638
Schlagwörter	Undergraduate Students; High School Students; Web Based Instruction; Science Instruction; Simulation; Genetics; Advanced Courses; Electronic Learning; Tutorial Programs; Metabolism; Achievement Gains; Handheld Devices + Suchen Sie Ihr Suchwort? High school; High schools; Student; Students; Oberschule; Schüler; Schülerin; Studentin; Web Based Training; Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Simulation program; Simulationsprogramm; Humangenetik; Fortgeschrittenenunterricht; Tutorial programmes; Förderprogramm; Lernprogramm; Tutorensystem; Stoffwechsel; Achievement gain; Leistungssteigerung
Abstract	Here, we describe a free, web-based simulation of the lac operon, "LacOp," that is designed to enhance the learning of prokaryotic gene regulation and pathways in advanced high school and undergraduate genetics courses. This new electronic resource was created by a team of students in an advanced undergraduate course and is hosted online (http://flask-env.rnwhymamqf.us-west-2.elasticbeanstalk.com/lacop). LacOp has a simple web interface compatible with a range of devices, including smartphones. To determine whether the LacOp simulation enhances student learning from traditional instruction, we introduced the lac operon to undergraduate genetics students through a traditional classroom experience followed by use of the LacOp simulation. Students worked on their own using the included tutorial to create and test the effect of various genotypes on "E. coli" lactose metabolism and regulation. Upon completion of the tutorial, students showed measurable gains in conceptual understanding of the lac operon. These students also reported a generally favorable opinion of the LacOP simulation as a use of their instructional time. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01