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Autor/inPeriyannan, Gopal R.
TitelBacterial Cellobiose Metabolism: An Inquiry-Driven, Comprehensive Undergraduate Laboratory Teaching Approach to Promote Investigative Learning
QuelleIn: Biochemistry and Molecular Biology Education, 47 (2019) 4, S.438-445 (8 Seiten)Infoseite zur Zeitschrift
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ZusatzinformationORCID (Periyannan, Gopal R.)
Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN1470-8175
DOI10.1002/bmb.21237
SchlagwörterUndergraduate Study; College Science; Biochemistry; Science Instruction; Science Laboratories; Laboratory Training; Metabolism; Laboratory Experiments; Molecular Biology; Inquiry
AbstractTechnique-centered biochemistry or molecular biology undergraduate laboratory curricula do not offer significant opportunities for thoughtful, in-depth exploration of the science to foster investigative learning. To demonstrate inclusion of inquiry-driven laboratory experiments into the undergraduate biochemistry and molecular biology curricula, a comprehensive set of laboratory experiments, covering several principles of biochemistry and molecular biology, have been developed under a single theme. The laboratory curriculum described here comprehensively investigates bacterial cellobiose metabolism using multiple biochemical, molecular biological (RNA isolation, RT-PCR, PCR, and enzyme assay), and analytical techniques (High Performance Liquid Chromatography, NMR, spectrophotometry, and thin-layer chromatography) to explore the principles of metabolomics and genomics in a single undergraduate laboratory course setting using Caulobacter crescentus as the model organism. This laboratory module serves as a model for educators to develop easy-to-implement laboratory curricula incorporating contemporary biochemistry and molecular biology concepts and techniques to provide a course-based undergraduate research experiences (CUREs) with defined learning objectives. © 2019 International Union of Biochemistry and Molecular Biology, 47(4):438--445, 2019. (As Provided).
AnmerkungenWiley-Blackwell. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8598; Fax: 781-388-8232; e-mail: cs-journals@wiley.com; Web site: http://www.wiley.com/WileyCDA
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2020/1/01
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