Exercise and Type 2 Diabetes: Molecular Mechanisms Regulating Glucose Uptake in Skeletal Muscle

Autor/inn/en	Stanford, Kristin I.; Goodyear, Laurie J.
Titel	Exercise and Type 2 Diabetes: Molecular Mechanisms Regulating Glucose Uptake in Skeletal Muscle
Quelle	In: Advances in Physiology Education, 38 (2014) 4, S.308-314 (6 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1043-4046
DOI	10.1152/advan.00080.2014
Schlagwörter	Exercise; Diabetes; Muscular Strength; Prevention; Physiology; Molecular Structure; Genetics; Metabolism + Suchen Sie Ihr Suchwort? Übung; Muskelkraft; Prävention; Vorbeugung; Physiologie; Humangenetik; Stoffwechsel
Abstract	Exercise is a well-established tool to prevent and combat type 2 diabetes. Exercise improves whole body metabolic health in people with type 2 diabetes, and adaptations to skeletal muscle are essential for this improvement. An acute bout of exercise increases skeletal muscle glucose uptake, while chronic exercise training improves mitochondrial function, increases mitochondrial biogenesis, and increases the expression of glucose transporter proteins and numerous metabolic genes. This review focuses on the molecular mechanisms that mediate the effects of exercise to increase glucose uptake in skeletal muscle. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10