Differential Brain Responses to Cries of Infants with Autistic Disorder and Typical Development: An fMRI Study

Autor/inn/en	Venuti, Paola; Caria, Andrea; Esposito, Gianluca; De Pisapia, Nicola; Bornstein, Marc H.; de Falco, Simona
Titel	Differential Brain Responses to Cries of Infants with Autistic Disorder and Typical Development: An fMRI Study
Quelle	In: Research in Developmental Disabilities: A Multidisciplinary Journal, 33 (2012) 6, S.2255-2264 (10 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0891-4222
DOI	10.1016/j.ridd.2012.06.011
Schlagwörter	Brain; Infants; Autism; Pervasive Developmental Disorders; Adults; Acoustics; Auditory Perception; Neurological Organization; Psychological Patterns + Suchen Sie Ihr Suchwort? Gehirn; Infant; Toddler; Toddlers; Kleinkind; Autismus; Akustik; Auditive Wahrnehmung; Akustische Wahrnehmung
Abstract	This study used fMRI to measure brain activity during adult processing of cries of infants with autistic disorder (AD) compared to cries of typically developing (TD) infants. Using whole brain analysis, we found that cries of infants with AD compared to those of TD infants elicited enhanced activity in brain regions associated with verbal and prosodic processing, perhaps because altered acoustic patterns of AD cries render them especially difficult to interpret, and increased activity in brain regions associated with emotional processing, indicating that AD cries also elicit more negative feelings and may be perceived as more aversive and/or arousing. Perceived distress engendered by AD cries related to increased activation in brain regions associated with emotional processing. This study supports the hypothesis that cry is an early and meaningful anomaly displayed by children with AD. It could be that cries associated with AD alter parent-child interactions much earlier than the time that reliable AD diagnosis normally occurs. (Contains 2 tables and 3 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10