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Autor/inn/enVidal, Julie; Mills, Travis; Pang, Elizabeth W.; Taylor, Margot J.
TitelResponse Inhibition in Adults and Teenagers: Spatiotemporal Differences in the Prefrontal Cortex
QuelleIn: Brain and Cognition, 79 (2012) 1, S.49-59 (11 Seiten)
PDF als Volltext Verfügbarkeit 
Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN0278-2626
DOI10.1016/j.bandc.2011.12.011
SchlagwörterInhibition; Adolescents; Spatial Ability; Cognitive Processes; Executive Function; Brain Hemisphere Functions; Responses; Task Analysis; Adults; Diagnostic Tests; Motor Reactions; Performance
AbstractInhibition is a core executive function reliant on the frontal lobes that shows protracted maturation through to adulthood. We investigated the spatiotemporal characteristics of response inhibition during a visual go/no-go task in 14 teenagers and 14 adults using magnetoencephalography (MEG) and a contrast between two no-go experimental conditions designed to eliminate a common confound in earlier studies comparing go with no-go trials. Source analyses were performed using an event-related beamformer algorithm with co-registered individual structural MRIs. Performance was controlled to be similar across subjects. Analyses of MEG data revealed bilateral prefrontal activity in the inhibitory condition for both age groups, but with different spatiotemporal patterns: around 300ms after stimulus onset in middle frontal gyri in teenagers vs. around 260ms in inferior frontal gyri in adults. Moreover, the inhibition of a prepotent motor response showed a stronger recruitment of the left hemisphere in teenagers than in adults and of the right hemisphere in adults than in teenagers. These findings provide high-resolution temporal and spatial information regarding response inhibition in adolescents compared to adults, independent of motor components and performance differences. (Contains 1 table and 5 figures.) (As Provided).
AnmerkungenElsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2017/4/10
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