Quality of Life in Patients with Multiple Sclerosis: The Impact of Depression, Fatigue, and Disability

Autor/inn/en	Goksel Karatepe, Altlnay; Kaya, Taciser; Gunaydn, Rezzan; Demirhan, Aylin; Ce, Plnar; Gedizlioglu, Muhtesem
Titel	Quality of Life in Patients with Multiple Sclerosis: The Impact of Depression, Fatigue, and Disability
Quelle	In: International Journal of Rehabilitation Research, 34 (2011) 4, S.290-298 (9 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0342-5282
DOI	10.1097/MRR.0b013e32834ad479
Schlagwörter	Emotional Problems; Fatigue (Biology); Employment Level; Physical Disabilities; Quality of Life; Diseases; Mental Health; Questionnaires; Patients; Correlation; Severity (of Disability); Measures (Individuals); Predictor Variables; Beck Depression Inventory + Suchen Sie Ihr Suchwort? Fatigue; Ermüdung; Beschäftigungsgrad; Physical handicap; Körperbehinderung; Lebensqualität; Disease; Krankheit; Psychohygiene; Fragebogen; Patient; Korrelation; Schweregrad; Messdaten; Prädiktor
Abstract	Aim: The aim of this study was to assess the quality of life (QoL) in patients with multiple sclerosis (MS), and to evaluate its association with disability and psychosocial factors especially depression and fatigue. Methods: Demographic characteristics, education level, disease severity, and disease duration were documented for each patient. QoL, fatigue level, cognitive status, and depression level of patients were assessed by Multiple Sclerosis Quality of Life-54, Fatigue Severity Scale, Mini Mental State Scale, and Beck Depression Inventory, respectively. Results: Seventy-nine patients with MS were included in the study. There was a moderate degree of impairment in the QoL scores of MS patients. The most affected parts of QoL were included: role limitation-related physical and emotional problems and physical and social functions. Both physical and mental health components of QoL showed a positive correlation with the educational level and employment status; a negative correlation with the level of disability, fatigue, and depression. Depression, disability level, and fatigue were the strongest variables associated with QoL, and the most important predictor of QoL was depression. Conclusion: Our results have shown that both physical and mental health components of QoL were negatively affected by MS. The most important predictor of QoL was depression followed by disability and fatigue. To improve the QoL for MS patients, in addition to physical disability, the influences of depression and fatigue on QoL should be taken into consideration. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10