Testing the Construct Validity of Proposed Criteria for "DSM-5" Autism Spectrum Disorder

Autor/inn/en	Mandy, William P. L.; Charman, Tony; Skuse, David H.
Titel	Testing the Construct Validity of Proposed Criteria for "DSM-5" Autism Spectrum Disorder
Quelle	In: Journal of the American Academy of Child & Adolescent Psychiatry, 51 (2012) 1, S.41-50 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0890-8567
DOI	10.1016/j.jaac.2011.10.013
Schlagwörter	Models; Autism; Construct Validity; Criteria; Factor Analysis; Pervasive Developmental Disorders; Children; Interviews; Comparative Analysis; Adolescents; Behavior Patterns; Repetition; Severity (of Disability); Verbal Ability + Suchen Sie Ihr Suchwort? Analogiemodell; Autismus; Faktorenanalyse; Child; Kind; Kinder; Interviewing; Interviewtechnik; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Wiederholung; Schweregrad; Mündliche Leistung
Abstract	Objective: To use confirmatory factor analysis to test the construct validity of the proposed "DSM-5" symptom model of autism spectrum disorder (ASD), in comparison to alternative models, including that described in "DSM-IV-TR." Method: Participants were 708 verbal children and young persons (mean age, 9.5 years) with mild to severe autistic difficulties. Autistic symptoms were measured using the Developmental, Dimensional and Diagnostic interview (3Di). The fit of the two-factor "DSM-5" model, which has a social communication and a restricted, repetitive behavior (RRB) factor, was compared with that of alternative models. In one half of the sample, properties of the "DSM-5" model were examined to investigate the validity of specific diagnostic criteria, informing the development of a better fitting "DSM-5" model. This was then cross-validated in the remaining "hold-out" half of the sample; and its stability was tested across groups defined by age, sex, and symptom severity. Results: The "DSM-5" model was superior to the three-factor "DSM-IV-TR" model. It was improved by the removal of items measuring "play and imagination" and "stereotyped and repetitive use of language." A scale measuring sensory abnormalities was added to the model, and loaded onto its RRB factor. This "DSM-5" model fit well in the hold-out sample; was stable across age and sex; and fit adequately in those with clinical and sub-threshold autistic presentations. Conclusions: Among higher-functioning individuals, ASD is a dyad, not a triad, with distinct social communication and repetitive behavior dimensions. As suggested in the proposed "DSM-5" criteria, sensory abnormalities are part of the RRB symptom cluster. (Contains 2 figures and 3 tables.) (As Provided).
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Update	2017/4/10