Literaturnachweis - Detailanzeige
| Autor/inn/en | Cornish, Kim M.; Savage, Robert; Hocking, Darren R.; Hollis, Chris P. |
|---|---|
| Titel | Association of the DAT1 Genotype with Inattentive Behavior Is Mediated by Reading Ability in a General Population Sample |
| Quelle | In: Brain and Cognition, 77 (2011) 3, S.453-458 (6 Seiten)
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| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 0278-2626 |
| DOI | 10.1016/j.bandc.2011.08.013 |
| Schlagwörter | Attention Deficit Hyperactivity Disorder; Age; Etiology; Reading Ability; Genetics; Correlation; Reading Difficulties; Biochemistry; Disabilities; Elementary School Students; Symptoms (Individual Disorders) |
| Abstract | Attention deficit hyperactivity disorder (ADHD) and reading disability (RD) frequently co-occur in the child population and therefore raise the possibility of shared genetic etiology. We used a quantitative trait loci (QTL) approach to assess the involvement of the dopamine transporter (DAT1) gene polymorphism in mediating reading disability and poor attention in a general population sample of primary school children aged 6-11 years in the UK. The potential confounding effects of IQ and chronological age were also investigated. We found an independent association between the homozygous DAT1 10/10 repeat genotype and RD that was not accounted for by the level of ADHD symptoms. This finding suggests that the DAT1 gene polymorphism may influence a common neural mechanism underlying both reading acquisition and ADHD symptoms. (Contains 1 figure and 1 table.) (As Provided). |
| Anmerkungen | Elsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2017/4/10 |
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