Impaired Finger Dexterity in Parkinson's Disease Is Associated with Praxis Function

Autor/inn/en	Vanbellingen, T.; Kersten, B.; Bellion, M.; Temperli, P.; Baronti, F.; Muri, R.; Bohlhalter, S.
Titel	Impaired Finger Dexterity in Parkinson's Disease Is Associated with Praxis Function
Quelle	In: Brain and Cognition, 77 (2011) 1, S.48-52 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0278-2626
DOI	10.1016/j.bandc.2011.06.003
Schlagwörter	Diseases; Pathology; Rating Scales; Patients; Multidimensional Scaling; Motor Reactions; Symptoms (Individual Disorders); Task Analysis; Human Body; Nonverbal Communication; Correlation; Brain Hemisphere Functions; Psychomotor Skills + Suchen Sie Ihr Suchwort? Disease; Krankheit; Pathologie; Rating-Skala; Patient; Mehrdimensionale Analysis; Psychiatrische Symptomatik; Aufgabenanalyse; Menschlicher Körper; Non-verbal communication; Nonverbale Kommunikation; Korrelation; Psychomotorische Aktivität
Abstract	A controversial concept suggests that impaired finger dexterity in Parkinson's disease may be related to limb kinetic apraxia that is not explained by elemental motor deficits such as bradykinesia. To explore the nature of dexterous difficulties, the aim of the present study was to assess the relationship of finger dexterity with ideomotor praxis function and parkinsonian symptoms. Twenty-five patients with Parkinson's disease participated in the study. Their left and right arms were tested independently. Testing was done in an OFF and ON state as defined by a modified version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS). Finger dexterity was assessed by a coin rotation (CR) task and ideomotor praxis using a novel test of upper limb apraxia (TULIA), in which the patients were requested to imitate and pantomime 48 meaningless, as well as communicative and tool-related gestures. Coin rotation significantly correlated with TULIA irrespective of the motor state and arm involved, but not with the MDS-UPDRS. This association was significantly influenced by Hoehn and Yahr stage. The strong association of finger dexterity with praxis function but not the parkinsonian symptoms indicates that impaired finger dexterity in Parkinson's disease may be indeed apraxic in nature, yet, predominantly in advanced stages of the disease when cortical pathology is expected to develop. The findings are discussed within a cognitive-motor model of praxis function. (Contains 3 tables.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10