An Extended Motor Network Generates Beta and Gamma Oscillatory Perturbations during Development

Autor/inn/en	Wilson, Tony W.; Slason, Erin; Asherin, Ryan; Kronberg, Eugene; Reite, Martin L.; Teale, Peter D.; Rojas, Donald C.
Titel	An Extended Motor Network Generates Beta and Gamma Oscillatory Perturbations during Development
Quelle	In: Brain and Cognition, 73 (2010) 2, S.75-84 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0278-2626
DOI	10.1016/j.bandc.2010.03.001
Schlagwörter	Neurological Impairments; Motor Reactions; Child Development; Task Analysis; Brain Hemisphere Functions; Statistical Analysis; Psychomotor Skills + Suchen Sie Ihr Suchwort? Neurodegenerative Erkrankung; Kindesentwicklung; Aufgabenanalyse; Statistische Analyse; Psychomotorische Aktivität
Abstract	This study examines the time course and neural generators of oscillatory beta and gamma motor responses in typically-developing children. Participants completed a unilateral flexion-extension task using each index finger as whole-head magnetoencephalography (MEG) data were acquired. These MEG data were imaged in the frequency-domain using spatial filtering and the resulting event-related synchronizations and desynchronizations (ERS/ERD) were subjected to voxel-wise statistical analyses to illuminate time-frequency specific activation patterns. Consistent with adult data, these children exhibited a pre-movement ERD that was strongest over the contralateral post-central gyrus, and a post-movement ERS response with the most prominent peak being in the contralateral precentral gyrus near premotor cortices. We also observed a high-frequency ([approximately equal to]80 Hz) ERS response that coincided with movement onset and was centered on the contralateral precentral gyrus, slightly superior and posterior to the beta ERS. In addition to pre- and post-central gyri activations, these children exhibited beta and gamma activity in supplementary motor areas (SMA) before and during movement, and beta activation in cerebellar cortices before and after movement. We believe the gamma synchronization may be an excellent candidate signal of basic cortical motor control, as the spatiotemporal dynamics indicate the primary motor cortex generates this response (and not the beta oscillations) which is closely yoked to the initial muscle activation. Lastly, these data suggest several additional neural regions including the SMA and cerebellum are involved in basic movements during development. (Contains 1 table and 7 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10