A Predictive Mathematical Model of Muscle Forces for Children with Cerebral Palsy

Autor/inn/en	Lee, Samuel C. K.; Ding, Jun; Prosser, Laura A.; Wexler, Anthony S.; Binder-Macleod, Stuart A.
Titel	A Predictive Mathematical Model of Muscle Forces for Children with Cerebral Palsy
Quelle	In: Developmental Medicine & Child Neurology, 51 (2009) 12, S.949-958 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0012-1622
DOI	10.1111/j.1469-8749.2009.03350.x
Schlagwörter	Intervention; Stimulation; Mathematical Models; Cerebral Palsy; Physiology; Human Body; Assistive Technology; Predictor Variables; Children; Early Adolescents; Psychomotor Skills; Prediction + Suchen Sie Ihr Suchwort? Mathematical model; Mathematisches Modell; Hirnlähmung; Physiologie; Menschlicher Körper; Prädiktor; Child; Kind; Kinder; Psychomotorische Aktivität; Vorhersage
Abstract	Aim: The purpose of this study was to determine if our previously developed muscle model could be used to predict forces of the quadriceps femoris and triceps surae muscles of children with spastic diplegic cerebral palsy (CP). Method: Twenty-two children with CP (12 males, 10 females; mean age 10y, SD 2y, range 7-13y; Gross Motor Function Classification System levels II and III) participated. A physiologically based mathematical model with four free parameters is presented. Results: For individuals with CP, the model predicted well the force profile throughout each contraction and both peak force and force-time integral responses to a wide range of stimulation frequencies (5-100Hz) and different stimulation patterns (constant-, variable-, and doublet-frequency trains) both for nonfatigued and fatigued muscles. Interpretation: The significance of this work is the insight the model can provide into the physiology of muscle in CP. Additionally, the model can potentially be applied clinically to design optimal electrical stimulation patterns for interventions to address impairments in strength and function in individuals with CP, such as functional electrical stimulation-assisted cycling. (As Provided).
Anmerkungen	Wiley-Blackwell. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8598; Fax: 781-388-8232; e-mail: cs-journals@wiley.com; Web site: http://www.wiley.com/WileyCDA/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10