Intelligence and Persisting with Medication for Two Years: Analysis in a Randomised Controlled Trial

Autor/inn/en	Deary, Ian J.; Gale, Catharine R.; Stewart, Marlene C. W.; Fowkes, F. Gerald R.; Murray, Gordon D.; Batty, G. David; Price, Jacqueline F.
Titel	Intelligence and Persisting with Medication for Two Years: Analysis in a Randomised Controlled Trial
Quelle	In: Intelligence, 37 (2009) 6, S.607-612 (6 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0160-2896
DOI	10.1016/j.intell.2009.01.001
Schlagwörter	Outcomes of Treatment; Measures (Individuals); Intelligence Quotient; Foreign Countries; Drug Therapy; Verbal Ability; Compliance (Psychology); At Risk Persons; Vocabulary; Scores; Health Behavior; Diseases; Persistence; Hypertension; Diagnostic Tests; United Kingdom (Scotland) + Suchen Sie Ihr Suchwort? Messdaten; Intelligenzquotient; Ausland; Mündliche Leistung; Risikogruppe; Wortschatz; Health behaviour; Gesundheitsverhalten; Disease; Krankheit; Ausdauer; Bluthochdruck; Hypertonie; Diagnostic test; Diagnostischer Test
Abstract	The study examined whether verbal intelligence is associated with persisting to take medication for up to two years. The design is a prospective follow-up of compliance with taking medication in high-risk individuals participating in a randomised, placebo-controlled trial set in Central Scotland. Participants were 1993 people aged between 50 and 77 years with an ankle brachial index less than or equal to 0.95. The medication was 100 mg aspirin or placebo daily. The principal outcome measure was continuing with taking medication or stopping it due to having "changed one's mind". Higher verbal intelligence was associated with a greater likelihood of continuing to take medication up to two years after randomisation. For a standard deviation increase in Mill Hill Vocabulary Scale score, risk of stopping medication in the first two years of the study was 0.75 (95% CI 0.64 to 0.87, p less than 0.001). Comparing the highest and lowest quartiles of IQ, the lowest IQ group's relative rate of stopping medication was 2.51 (95% CI 1.52 to 4.22). The effect was not attenuated after adjustment for sex, smoking, or level of deprivation. Verbal intelligence is associated with continuing, medium-to-long term engagement with health self-care, even in the face of uncertainty about whether active treatment is being received, whether the treatment is known to be effective in general, and whether it will be helpful to the individual taking it. Such persisting with potentially helpful health behaviours in the face of uncertainty might partly explain why people with higher intelligence live longer and suffer less morbidity from chronic diseases. (Contains 2 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10