The Semantic Simon Effect in Tourette's Syndrome and Obsessive-Compulsive Disorder

Autor/inn/en	Rankins, D.; Bradshaw, J. L.; Georgiou-Karistianis, N.
Titel	The Semantic Simon Effect in Tourette's Syndrome and Obsessive-Compulsive Disorder
Quelle	In: Brain and Cognition, 61 (2006) 3, S.225-234 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0278-2626
DOI	10.1016/j.bandc.2006.01.002
Schlagwörter	Neurological Impairments; Patients; Cognitive Processes; Inhibition; Neuropsychology; Clinical Diagnosis; Semantics; Symptoms (Individual Disorders); Comparative Analysis; Stimuli + Suchen Sie Ihr Suchwort? Neurodegenerative Erkrankung; Patient; Cognitive process; Kognitiver Prozess; Hemmung; Neuropsychologie; Semantik; Psychiatrische Symptomatik; Anreizsystem
Abstract	Core symptoms of Tourette's syndrome (TS) and obsessive-compulsive disorder (OCD) may be attributed to an impairment in inhibitory control. Neuropsychological studies have addressed inhibition in both disorders, but findings have been inconsistent. The aim of this study was to examine cognitive inhibition, using a semantic Simon effect paradigm, in patients with TS and OCD. Furthermore, to address comorbidity a group of TS + OCD patients was also examined. Results indicated that patients with TS and OCD were affected by the inhibitory components of the task. TS groups performed similarly to controls on simple and choice RT tasks, but were particularly compromised as increasingly complex inhibitory demands were imposed. OCD patients were slower and committed more errors than controls, especially in the more cognitively demanding conditions, and were particularly disadvantaged by incongruent stimulus-response compatibilities. Findings implicate possible fronto-striatal dysfunction, are consistent with previously reported inhibitory deficits in TS and OCD, and support the theory that comorbid TS + OCD is more closely linked to pure TS than OCD. (Author).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10