Staring Spells in Children with Autism Spectrum Disorder: A Clinical Dilemma

Autor/inn/en	Goenka, Ajay; Fonseca, Laura D.; Yu, Sarah G.; George, Monica C.; Wong, Caroline; Stolfi, Adrienne; Kumar, Gogi
Titel	Staring Spells in Children with Autism Spectrum Disorder: A Clinical Dilemma
Quelle	In: Autism: The International Journal of Research and Practice, 27 (2023) 5, S.1407-1416 (10 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Fonseca, Laura D.)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/13623613221137240
Schlagwörter	Children; Early Adolescents; Autism Spectrum Disorders; Clinical Diagnosis; Seizures; Symptoms (Individual Disorders); Patients; Epilepsy; Ohio (Dayton) + Suchen Sie Ihr Suchwort? Child; Kind; Kinder; Autism; Autismus; Anfallsleiden; Psychiatrische Symptomatik; Patient; Epilepsie
Abstract	To assess the role of clinical features in diagnosing seizures in children with autism spectrum disorder who present with staring spells. A 10-year retrospective chart analysis of autism spectrum disorder patients aged 3-14 years was performed at a tertiary care children's hospital. Patient demographics, clinical presentation, and epileptic seizure versus non-epileptic spell diagnosis were assessed. Target episodes of staring spells were captured during a long-term electroencephalogram monitoring record. Multilevel likelihood ratios and a receiver operating characteristic curve were determined using 8 of the 11 clinical variables. Among the cohort of 140 patients with autism spectrum disorder, 16% were diagnosed with epileptic seizures with the most common seizure being atypical absence seizures (64%). Clinical semiology differed between those diagnosed with epileptic seizures versus those diagnosed with non-epileptic spells in the average duration of episodes (42 s vs 87 s), frequency of spells per week (6 vs 11.5 spells), increase in frequency of staring spells over time (100% vs 40%), and response to verbal stimulation (0% vs 100%), respectively. Multilevel likelihood ratios based on the receiver operating characteristic curves and clinical semiology features may be helpful in differentiating epileptic seizures from non-epileptic spells in children with autism spectrum disorder. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01