Developmental Skills of Individuals with Angelman Syndrome Assessed Using the Bayley-III

Autor/inn/en	Sadhwani, Anjali; Wheeler, Anne; Gwaltney, Angela; Peters, Sarika U.; Barbieri-Welge, Rene L.; Horowitz, Lucia T.; Noll, Lisa M.; Hundley, Rachel J.; Bird, Lynne M.; Tan, Wen-Hann
Titel	Developmental Skills of Individuals with Angelman Syndrome Assessed Using the Bayley-III
Quelle	In: Journal of Autism and Developmental Disorders, 53 (2023) 2, S.720-737 (18 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Sadhwani, Anjali)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-020-04861-1
Schlagwörter	Child Development; Developmental Disabilities; Psychomotor Skills; Infants; Toddlers; Scores; Genetic Disorders; Bayley Scales of Infant and Toddler Development + Suchen Sie Ihr Suchwort? Kindesentwicklung; Entwicklungsstörung; Psychomotorische Aktivität; Infant; Toddler; Toddlers; Kleinkind; Infants
Abstract	We describe the development of 236 children with Angelman syndrome (AS) using the Bayley Scales of Infant and Toddler Development, Third Edition. Multilevel linear mixed modeling approaches were used to explore differences between molecular subtypes and over time. Individuals with AS continue to make slow gains in development through at least age 12 years of age at about 1-2 months/year based on age equivalent score and 1-16 growth score points/year depending on molecular subtype and domain. Children with a deletion have lower scores at baseline and slower rate of gaining skills while children with "UBE3A" variant subtype demonstrated higher scores as well as greater rates of skill attainment in all domains. The developmental profiles of UPD and ImpD were similar. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01