Association between Exposure of Children to General Anesthesia and Autism Spectrum Disorder

Autor/inn/en	Laporta, Mariana L.; Sprung, Juraj; Fejedelem, Caroline A.; Henning, Dustin T.; Weaver, Amy L.; Hanson, Andrew C.; Schroeder, Darrell R.; Myers, Scott M.; Voigt, Robert G.; Weingarten, Toby N.; Flick, Randall P.; Warner, David O.
Titel	Association between Exposure of Children to General Anesthesia and Autism Spectrum Disorder
Quelle	In: Journal of Autism and Developmental Disorders, 52 (2022) 10, S.4301-4310 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-021-05305-0
Schlagwörter	Anesthesiology; Autism Spectrum Disorders; Correlation; Infants; Toddlers; Incidence; Case Studies; Comparative Analysis; Matched Groups; Birth; Body Weight; Child Health; Risk; Minnesota + Suchen Sie Ihr Suchwort? Anästhesie; Autism; Autismus; Korrelation; Infant; Toddler; Toddlers; Kleinkind; Infants; Vorkommen; Case study; Fallstudie; Case Study; Geburt; Körpergewicht; Risiko
Abstract	This study tested the hypothesis that exposure of children prior to their third birthday to procedures requiring general anesthesia is associated with an increased incidence of autism spectrum disorder (ASD) in later life. This study employed a nested, 1:2 matched-case control study design using ASD cases identified in a population-based birth cohort of children born in Olmsted County, MN from 1976 to 2000. Matching variables included sex, date of birth, and mother's age in conditional logistic regression including 499 ASD cases and 998 controls. After adjusting for birth weight and health status, there was no significant association between exposure and ASD (OR 1.27 [95% CI 0.92-1.76]), indicating that general anesthesia is not associated with an increased risk of ASD. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01