Differences in Learning and Memory between Middle-Aged Female and Male Rats

Autor/inn/en	Colettis, Natalia Claudia; Habif, Martín; Oberholzer, María Victoria; Filippin, Federico; Jerusalinsky, Diana Alicia
Titel	Differences in Learning and Memory between Middle-Aged Female and Male Rats
Quelle	In: Learning & Memory, 29 (2022) 5, S.120-125 (6 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Colettis, Natalia Claudia) ORCID (Habif, Martín) ORCID (Oberholzer, María Victoria)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
Schlagwörter	Gender Differences; Adults; Animals; Cognitive Processes; Long Term Memory; Short Term Memory + Suchen Sie Ihr Suchwort? Geschlechterkonflikt; Animal; Tier; Tiere; Cognitive process; Kognitiver Prozess; Langzeitgedächtnis; Kurzzeitgedächtnis
Abstract	We observed differences in cognitive functions between middle-aged female and male Wistar rats. Both (like youngsters) discriminated new versus familiar objects, showing similar short- and long-term memory (STM and LTM, respectively). Only females show robust LTM for new location of an object. Both successfully form LTM of inhibitory avoidance, though males appeared to be amnesic for memory persistence. Habituation, locomotion, horizontal exploration, "stereotypies," fear, and anxiety-like behavior were similar for both, while vertical exploration was significantly higher in middle-aged and younger females. Therefore, sex-dependent differences in some cognitive functions and behaviors must be considered when designing and interpreting learning and memory studies. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://learnmem.cshlp.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01