The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder

Autor/inn/en	DeMayo, Marilena M.; Pokorski, Izabella; Song, Yun J. C.; Thapa, Rinku; Patel, Shrujna; Ambarchi, Zahava; Soligo, Domenic; Sadeli, Indra; Thomas, Emma E.; Hickie, Ian B.; Guastella, Adam J.
Titel	The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder
Quelle	In: Journal of Autism and Developmental Disorders, 52 (2022) 3, S.1211-1222 (12 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Guastella, Adam J.)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-021-05028-2
Schlagwörter	Diagnostic Tests; Brain; Medicine; Autism; Pervasive Developmental Disorders; Children; Outcomes of Treatment; Clinical Diagnosis + Suchen Sie Ihr Suchwort? Diagnostic test; Diagnostischer Test; Gehirn; Medizin; Autismus; Child; Kind; Kinder
Abstract	There is an increasing interest in using magnetic resonance imaging (MRI) as a tool for precision medicine in autism spectrum disorder (ASD). This study investigated the feasibility of MRI scanning in a large comprehensive, inclusive and test heavy clinical trial for children (aged 3-12 years) with ASD, without functioning constraints for participation. Of the 71 participants enrolled who consented to the MRI, 24 participants (38%) successfully completed an MRI scan at baseline along with other assessments. This scanning followed a familiarization procedure at two preceding visits. At post-treatment, 21 participants successfully completed the MRI scan. This study highlights the challenge of completing MRI assessments in ASD populations when conducted as one of a number of tests in a clinical trial. (As Provided).
Anmerkungen	Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01