Co-Occurrence of Hypernasality and Voice Impairment in Amyotrophic Lateral Sclerosis: Acoustic Quantification

Autor/inn/en	Eshghi, Marziye; Connaghan, Kathryn P.; Gutz, Sarah E.; Berry, James D.; Yunusova, Yana; Green, Jordan R.
Titel	Co-Occurrence of Hypernasality and Voice Impairment in Amyotrophic Lateral Sclerosis: Acoustic Quantification
Quelle	In: Journal of Speech, Language, and Hearing Research, 64 (2021) 12, S.4772-4783 (12 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Eshghi, Marziye) ORCID (Connaghan, Kathryn P.) ORCID (Gutz, Sarah E.) ORCID (Yunusova, Yana) ORCID (Green, Jordan R.)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1092-4388
Schlagwörter	Neurological Impairments; Articulation Impairments; Acoustics; Measurement Techniques; Voice Disorders; Adults; Symptoms (Individual Disorders) + Suchen Sie Ihr Suchwort? Neurodegenerative Erkrankung; Artikulationsstörung; Akustik; Messtechnik; Stimmstörung; Psychiatrische Symptomatik
Abstract	Purpose: Hypernasality and atypical voice characteristics are common features of dysarthric speech due to amyotrophic lateral sclerosis (ALS). Existing acoustic measures have been developed to primarily target either hypernasality or voice impairment, and the effects of co-occurring hypernasality-voice problems on these measures are unknown. This report explores (a) the extent to which acoustic measures are affected by concurrent perceptually identified hypernasality and voice impairment due to ALS and (b) candidate acoustic measures of early indicators of hypernasality and voice impairment in the presence of multisystem involvement in individuals with ALS. Method: Two expert listeners rated severity of hypernasality and voice impairment in sentences produced by individuals with ALS (n = 27). The samples were stratified based on perceptual ratings: voice/hypernasality asymptomatic, predominantly hypernasal, predominantly voice impairment, and mixed (co-occurring hypernasality and voice impairment). Groups were compared using established acoustic measures of hypernasality (one-third octave analysis) and voice (cepstral/spectral analysis) impairment. Results: The one-third octave analysis differentiated all groups; the cepstral peak prominence differentiated all groups except asymptomatic versus mixed, whereas the low-to-high spectral ratio did not differ among groups. Additionally, one-third octave analyses demonstrated promising speech diagnostic potential. Conclusions: The results highlight the need to consider the validity of measures in the context of multisubsystem involvement. Our preliminary findings further suggest that the one-third octave analysis may be an optimal approach to quantify hypernasality and voice abnormalities in the presence of multisystem speech impairment. Future evaluation of the diagnostic accuracy of the one-third octave analysis is warranted. (As Provided).
Anmerkungen	American Speech-Language-Hearing Association. 2200 Research Blvd #250, Rockville, MD 20850. Tel: 301-296-5700; Fax: 301-296-8580; e-mail: slhr@asha.org; Web site: http://jslhr.pubs.asha.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01