Systematic Review of Prenatal Exposure to Endocrine Disrupting Chemicals and Autism Spectrum Disorder in Offspring

Autor/inn/en	Marí-Bauset, Salvador; Peraita-Costa, Isabel; Donat-Vargas, Carolina; Llopis-González, Agustín; Marí-Sanchis, Amelia; Llopis-Morales, Juan; Morales Suárez-Varela, María
Titel	Systematic Review of Prenatal Exposure to Endocrine Disrupting Chemicals and Autism Spectrum Disorder in Offspring
Quelle	In: Autism: The International Journal of Research and Practice, 26 (2022) 1, S.6-32 (27 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Marí-Bauset, Salvador) ORCID (Morales Suárez-Varela, María)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/13623613211039950
Schlagwörter	Autism; Pervasive Developmental Disorders; Epidemiology; Prenatal Influences; Hazardous Materials; Poisoning; Research; Research Methodology; Physiology; Mothers; Gender Differences; Asperger Syndrome; Metabolism; Autism Diagnostic Observation Schedule + Suchen Sie Ihr Suchwort? Autismus; Epidemiologie; Pränataler Einfluss; Hazardous substance; Gefahrstoff; Forschung; Research method; Forschungsmethode; Physiologie; Mother; Mutter; Geschlechterkonflikt; Asperger-Syndrom; Stoffwechsel
Abstract	Epidemiological studies, which can have inherent methodological limitations, are used to study the relation between endocrine disrupting chemicals and autism spectrum disorder. The objective is to systematically review the treatment of methodological limitations and assess the quality and strength of the findings in the available literature. The quality and strength of the evidence were evaluated using the Navigation Guide Systematic Review Methodology. The overall quality and strength of the available studies were "moderate" and "limited," respectively. Risk of bias due to the methodological limitations regarding the exclusion of potential confounding factors and the lack of accuracy of exposure assessment methods were the most prevalent and were also considered to arrive at these results. The omnipresence of endocrine disrupting chemicals, their persistence and bioaccumulation, and the biological plausibility of the association between prenatal exposure to these and later development of autism spectrum disorder highlight the need to carry out well-designed epidemiological studies that overcome the methodological limitations observed in the currently available literature in order to be able to inform public policy to prevent exposure to these potentially harmful chemicals. (As Provided).
Anmerkungen	SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01