Literaturnachweis - Detailanzeige
| Autor/inn/en | Simsek, Fulya; Isik, Ümit; Aktepe, Evrim; Kiliç, Faruk; Sirin, Fevziye Burcu; Bozkurt, Mustafa |
|---|---|
| Titel | Comparison of Serum VEGF, IGF-1, and HIF-1[alpha] Levels in Children with Autism Spectrum Disorder and Healthy Controls |
| Quelle | In: Journal of Autism and Developmental Disorders, 51 (2021) 10, S.3564-3574 (11 Seiten)
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| Zusatzinformation | ORCID (Simsek, Fulya) ORCID (Isik, Ümit) ORCID (Aktepe, Evrim) ORCID (Kiliç, Faruk) ORCID (Sirin, Fevziye Burcu) |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 0162-3257 |
| DOI | 10.1007/s10803-020-04820-w |
| Schlagwörter | Autism; Pervasive Developmental Disorders; Children; Preadolescents; Pathology; Metabolism; Physiology |
| Abstract | The aim of this study was to determine whether serum VEGF, IGF-1, and HIF-1[alpha] levels differed between Autism Spectrum Disorder (ASD) patients and healthy controls. A total of 40 children with ASD and 40 healthy controls aged 4-12 years were included. Serum levels of VEGF, IGF-1, and HIF-1[alpha] were measured using commercial enzyme-linked immunosorbent assay kits. Serum IGF-1 levels were found to be statistically significantly higher in the ASD group than in the control group. Serum HIF-1-[alpha] levels were borderline significantly lower in the ASD group. There was no statistically significant difference in serum VEGF levels between the two groups. IGF-1 and HIF-1[alpha] may play a potential role in the etiopathogenesis of ASD. (As Provided). |
| Anmerkungen | Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2024/1/01 |
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