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Autor/inn/enBishop, Lauren; McLean, Kiley J.; Rubenstein, Eric
TitelEpilepsy in Adulthood: Prevalence, Incidence, and Associated Antiepileptic Drug Use in Autistic Adults in a State Medicaid System
QuelleIn: Autism: The International Journal of Research and Practice, 25 (2021) 3, S.831-839 (9 Seiten)
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ZusatzinformationORCID (Bishop, Lauren)
ORCID (Rubenstein, Eric)
Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN1362-3613
DOI10.1177/1362361320942982
SchlagwörterEpilepsy; Autism; Pervasive Developmental Disorders; Incidence; Drug Therapy; Adults; Intellectual Disability; Comorbidity; Gender Differences; At Risk Persons; Individual Characteristics; Age Differences; Wisconsin
AbstractAlthough epilepsy commonly presents with autism in children, it is currently unknown whether established estimates represent the prevalence and incidence of epilepsy in autistic adults. Our objective was to use population-level Medicaid data to determine prevalence, incidence, and antiepileptic drug use associated with epilepsy in a unique population of autistic adults aged 21+ with (N = 2738) and without (N = 4775) intellectual disability and to compare results to adults with intellectual disability alone (N = 18,429). We found that 34.6% of autistic adults with intellectual disability and 11.1% of autistic adults without intellectual disability had epilepsy, compared to 27.0% of adults with intellectual disability alone. New incidence of epilepsy was 23.6 incident cases per 1000 person years (95% confidence interval: 21.3, 26.2) in autistic adults with intellectual disability, 7.7 incident cases per 1000 person years (95% confidence interval: 6.6, 8.9) in autistic adults without intellectual disability, and 15.9 incident cases per 1000 person years (95% confidence interval: 15.2, 16.7) in adults with intellectual disability alone. Female sex and intellectual disability were associated with increased risk of prevalent and incident epilepsy in autistic adults. Findings underscore the importance of treating prevalent epilepsy and screening and preventing incident epilepsy in autistic adults as they age. (As Provided).
AnmerkungenSAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2024/1/01
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