The Separate and Combined Effects of a Dangerous Context and an Epinephrine Injection on Sensory Preconditioning in Rats

Autor/inn/en	Kikas, Katarina; Westbrook, R. Frederick; Holmes, Nathan M.
Titel	The Separate and Combined Effects of a Dangerous Context and an Epinephrine Injection on Sensory Preconditioning in Rats
Quelle	In: Learning & Memory, 28 (2021) 4, S.114-125 (12 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.052324.120
Schlagwörter	Sensory Experience; Conditioning; Animals; Visual Stimuli; Experiments; Attention; Short Term Memory; Associative Learning; Pharmacology + Suchen Sie Ihr Suchwort? Sinnerfahrung; Animal; Tier; Tiere; Erprobung; Aufmerksamkeit; Kurzzeitgedächtnis; Arzneikunde
Abstract	Four experiments examined the effects of a dangerous context and a systemic epinephrine injection on sensory preconditioning in rats. In each experiment, rats were exposed to presentations of a tone and light in stage 1, light-shock pairings in stage 2, and test presentations of the tone alone and light alone in stage 3. Presentations of the tone and light in stage 1 occurred in either a safe or a previously shocked context, and/or under a systemic injection of epinephrine. Experiment 1 showed that a trace interval of 20 sec between presentations of the tone and light produced sensory preconditioning of the tone in a previously shocked context but not in a safe context, while experiment 2 provided evidence that this trace preconditioning was associative, due to the formation of a tone-light association. Experiment 3 showed that, in a safe context, exposure to the trace protocol under the influence of an epinephrine injection also produced sensory preconditioning of the tone, while experiment 4 provided evidence that a shocked context and an epinephrine injection have additive effects on trace preconditioning. These findings are discussed in relation to theories of trace conditioning. They suggest that the release of epinephrine by danger enhances attention and/or working memory processes, and thereby associative formation across a trace interval. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://learnmem.cshlp.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01