Evaluation of Appetite-Regulating Hormones in Young Children with Autism Spectrum Disorder

Autor/inn/en	Çelikkol Sadiç, Çagla; Bilgiç, Ayhan; Kilinç, Ibrahim; Oflaz, Mehmet Burhan; Baysal, Tamer
Titel	Evaluation of Appetite-Regulating Hormones in Young Children with Autism Spectrum Disorder
Quelle	In: Journal of Autism and Developmental Disorders, 51 (2021) 2, S.632-643 (12 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Çelikkol Sadiç, Çagla)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-020-04579-0
Schlagwörter	Young Children; Autism; Pervasive Developmental Disorders; Toddlers; Metabolism; Physiology; Severity (of Disability); Eating Disorders; Biochemistry + Suchen Sie Ihr Suchwort? Frühe Kindheit; Autismus; Infant; Infants; Toddler; Kleinkind; Stoffwechsel; Physiologie; Schweregrad; Appetite disorder; Essstörung; Biochemie
Abstract	This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01