Dysbiosis of Gut Fungal Microbiota in Children with Autism Spectrum Disorders

Autor/inn/en	Zou, Rong; Wang, Yuezhu; Duan, Mengmeng; Guo, Min; Zhang, Qiang; Zheng, Huajun
Titel	Dysbiosis of Gut Fungal Microbiota in Children with Autism Spectrum Disorders
Quelle	In: Journal of Autism and Developmental Disorders, 51 (2021) 1, S.267-275 (9 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Zheng, Huajun)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-020-04543-y
Schlagwörter	Children; Autism; Pervasive Developmental Disorders; Human Body; Diseases; Microbiology + Suchen Sie Ihr Suchwort? Child; Kind; Kinder; Autismus; Menschlicher Körper; Disease; Krankheit; Mikrobiologie
Abstract	In this study, we tested the feces of children with ASD and those of healthy children, and the overall changing of the community was observed in ASD children compared with controls. However, there were no abundant fungi populations showed significant variations between the ASD and Control group both at phylum and class level. Among the 507 genera identified, "Saccharomyces" and "Aspergillus" showed significant differences between ASD (59.07%) and Control (40.36%), indicating that they may be involved in the abnormal gut fungal community structure of ASD. When analyzed at the species level, a decreased abundance in "Aspergillus versicolor" was observed while "Saccharomyces cerevisiae" was increased in children with ASD relative to controls. Overall, this study characterized the fungal microbiota profile of children with ASD and identified potential diagnostic species closely related to the immune response in ASD. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01