Understanding the Uniqueness of Artocarpus Flavonoids: Isolation and Structure Elucidation of Cycloartocarpin from the Roots of "Artocarpus altilis"

Autor/inn/en	Hakim, Aliefman; Jufri, A. Wahab; Jamaluddin; Supriadi; Mutmainnah, Putri Ayu
Titel	Understanding the Uniqueness of Artocarpus Flavonoids: Isolation and Structure Elucidation of Cycloartocarpin from the Roots of "Artocarpus altilis"
Quelle	In: Journal of Chemical Education, 97 (2020) 11, S.4133-4136 (4 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Hakim, Aliefman)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9584
Schlagwörter	Science Instruction; College Science; Organic Chemistry; Science Laboratories; Hands on Science; Science Experiments; Laboratory Experiments; Undergraduate Students; Plants (Botany) + Suchen Sie Ihr Suchwort? Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Organische Chemie; Laboratory work; Laborarbeit; Pflanze
Abstract	Secondary metabolite compounds contained in each plant genus have certain characteristics, which is true also of the flavonoid in the genus "Artocarpus." In the experiment described here, third-year undergraduate students performed the isolation and characterization of cycloartocarpin from the roots of "Artocarpus altilis" (commonly known as breadfruit), giving them experience in skills such as extraction, fractionation, purification, and the structural elucidation of cycloartocarpin. Manipulation of the liquor by thin-layer and gravitation column chromatographic techniques proved to be a simple method to isolate cycloartocarpin. The flavonoid structure, cycloartocarpin, was treated with structure elucidation 1- and 2-dimensional NMR and infrared spectrometry. Students then compared the structure of the cycloartocarpin obtained with that of other flavonoids from the genus "Artocarpus" and other plant genera. From these comparisons, they were able to formulate structural characteristics of the flavonoid compounds of the genus "Artocarpus." The laboratory method, accomplished in four, 3 h laboratory sessions, allowed students to readily understand the process of isolating flavonoids and their peculiarities. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01