Autism with and without Regression: A Two-Year Prospective Longitudinal Study in Two Population-Derived Swedish Cohorts

Autor/inn/en	Thompson, Lucy; Gillberg, Christopher; Landberg, Sara; Kantzer, Anne-Katrin; Miniscalco, Carmela; Barnevik Olsson, Martina; Eriksson, Mats A.; Fernell, Elisabeth
Titel	Autism with and without Regression: A Two-Year Prospective Longitudinal Study in Two Population-Derived Swedish Cohorts
Quelle	In: Journal of Autism and Developmental Disorders, 49 (2019) 6, S.2281-2290 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-018-03871-4
Schlagwörter	Autism; Pervasive Developmental Disorders; Genetics; Symptoms (Individual Disorders); Severity (of Disability); Intellectual Disability; Language Impairments; Etiology; Young Children; Longitudinal Studies; Cohort Analysis; Foreign Countries; Sweden + Suchen Sie Ihr Suchwort? Autismus; Humangenetik; Psychiatrische Symptomatik; Schweregrad; Intellect; Disability; Disabilities; Verstand; Behinderung; Speech disorder; Speech disorders; Speech disabilities; Speech disability; Speech handicap; Speech handicaps; Speech impairment; Speech impairments; Language handicaps; Sprachbehinderung; Ätiologie; Frühe Kindheit; Longitudinal study; Longitudinal method; Longitudinal methods; Längsschnittuntersuchung; Kohortenanalyse; Ausland; Schweden
Abstract	Two community-based cohorts of children with autism spectrum disorder, examined using similar assessment protocols, were pooled (n = 301) and subdivided according to history of regression. Those with regression (n = 62), 20.5% of the combined cohort, were contrasted with those without regression (n = 241) at first assessment (age range 19-60 months) and at 2-year follow-up on a range of measures. The regression group was significantly more functionally impaired, with regard to intellectual function (p < .001), language development (p < 0.001), and to severity of autism (p < 0.01) at both T1 and T2. Only 14 (23.3%) had a clearly identified underlying etiology [24 (18.6%) in the non-regressive group]. There were no significant differences between those who had regressed 'from normal' and those who had regressed 'from low' functioning. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01