Literaturnachweis - Detailanzeige
Autor/inn/en | Mullins, Joseph J.; Prusinowski, Allen F. |
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Titel | Microwave-Promoted Synthesis of a Carbocyclic Curcuminoid: An Organic Chemistry Laboratory Experiment |
Quelle | In: Journal of Chemical Education, 96 (2019) 3, S.606-609 (4 Seiten)Infoseite zur Zeitschrift
PDF als Volltext |
Zusatzinformation | ORCID (Mullins, Joseph J.) |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 0021-9584 |
DOI | 10.1021/acs.jchemed.8b00662 |
Schlagwörter | Organic Chemistry; Laboratory Experiments; Undergraduate Students; Scientific Concepts; Radiation; College Science; Hands on Science |
Abstract | A microwave-promoted synthesis of a carbocyclic curcuminoid has been developed for the undergraduate organic chemistry laboratory curriculum. The experiment features several teaching points: A novel Knoevenagel iminium-mediated condensation forms a highly conjugated, intensely colored natural product. Reaction occurs uniquely at the less acidic positions of the diketone owing to the formation of a boron enolate formed in situ. Green chemistry is demonstrated by the use of microwave irradiation for efficient reaction, minimal use of solvent, and rapid and convenient workup conditions. Students from multiple lab sections obtained the product in good yield and purity and submitted reports containing their results and conclusions. (As Provided). |
Anmerkungen | Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2020/1/01 |