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Autor/inn/enO'Leary, Lisa; Hughes-McCormack, Laura; Dunn, Kirsty; Cooper, Sally-Ann
TitelEarly Death and Causes of Death of People with Down Syndrome: A Systematic Review
QuelleIn: Journal of Applied Research in Intellectual Disabilities, 31 (2018) 5, S.687-708 (22 Seiten)Infoseite zur Zeitschrift
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ZusatzinformationORCID (O'Leary, Lisa)
ORCID (Hughes-McCormack, Laura)
ORCID (Dunn, Kirsty)
ORCID (Cooper, Sally-Ann)
Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN1360-2322
DOI10.1111/jar.12446
SchlagwörterDeath; Down Syndrome; Ethnicity; Research Needs; Mortality Rate; Heart Disorders; Age; Comorbidity; Birth; Body Weight; Mothers; Parent Background; Educational Attainment; Race
AbstractBackground: It is thought that people with Down syndrome die younger than the general population, but that survival rates are improving. Methods: Five databases were searched for keywords related to intellectual disabilities, Down syndrome and mortality. Strict inclusion criteria were applied. Information from 34 selected studies was tabulated, extracted and synthesized. Results: People with Down syndrome died about 28 years younger than the general population. Congenital heart anomalies, comorbidities, low birthweight, and Black and minority ethnicity influenced earlier age of death, as did younger maternal age and poorer parental education. Congenital heart anomalies and respiratory conditions were the leading causes of death, and more common than in the general population. Survival rates have improved over time, particularly for those with congenital heart anomalies. Conclusions: People with Down syndrome are living longer but still die younger of different causes than the general population. More robust comparative data are needed, and ethnic differences require further study. (As Provided).
AnmerkungenWiley-Blackwell. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8598; Fax: 781-388-8232; e-mail: cs-journals@wiley.com; Web site: http://www.wiley.com/WileyCDA
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2020/1/01
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