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Autor/inn/enEdwards, Laura A.; Wagner, Jennifer B.; Tager-Flusberg, Helen; Nelson, Charles A.
TitelDifferences in Neural Correlates of Speech Perception in 3 Month Olds at High and Low Risk for Autism Spectrum Disorder
QuelleIn: Journal of Autism and Developmental Disorders, 47 (2017) 10, S.3125-3138 (14 Seiten)
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Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN0162-3257
DOI10.1007/s10803-017-3222-1
SchlagwörterAutism; Pervasive Developmental Disorders; Spectroscopy; Infants; Neurological Organization; Language Acquisition; At Risk Persons; Genetic Disorders; Diagnostic Tests; Auditory Stimuli; Syllables; Brain Hemisphere Functions; Females; Repetition; Habituation; Speech
AbstractIn this study, we investigated neural precursors of language acquisition as potential endophenotypes of autism spectrum disorder (ASD) in 3-month-old infants at high and low familial ASD risk. Infants were imaged using functional near-infrared spectroscopy while they listened to auditory stimuli containing syllable repetitions; their neural responses were analyzed over left and right temporal regions. While female low risk infants showed initial neural activation that decreased over exposure to repetition-based stimuli, potentially indicating a habituation response to repetition in speech, female high risk infants showed no changes in neural activity over exposure. This finding may indicate a potential neural endophenotype of language development or ASD specific to females at risk for the disorder. (As Provided).
AnmerkungenSpringer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2020/1/01
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