Dissociation between Complete Hippocampal Context Memory Formation and Context Fear Acquisition

Autor/inn/en	Leake, Jessica; Zinn, Raphael; Corbit, Laura; Vissel, Bryce
Titel	Dissociation between Complete Hippocampal Context Memory Formation and Context Fear Acquisition
Quelle	In: Learning & Memory, 24 (2017) 4, S.153-157 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.044578.116
Schlagwörter	Fear; Memory; Animals; Context Effect; Conditioning; Comparative Analysis; Time; Brain + Suchen Sie Ihr Suchwort? Furcht; Gedächtnis; Animal; Tier; Tiere; Zeit; Gehirn
Abstract	Rodents require a minimal time period to explore a context prior to footshock to display plateau-level context fear at test. To investigate whether this rapid fear plateau reflects complete memory formation within that short time-frame, we used the immediate-early gene product Arc as an indicator of hippocampal context memory formation-related activity. We found that hippocampal Arc expression continued to increase well past the minimal time required for plateau-level fear. This raises the possibility that context fear conditioning occurs more rapidly than complete memory formation. Thus, animals may be able to condition robustly to both complete and incomplete contextual representations. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01