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Autor/inn/enWhyte, Elisabeth M.; Behrmann, Marlene; Minshew, Nancy J.; Garcia, Natalie V.; Scherf, K. Suzanne
TitelAnimal, but Not Human, Faces Engage the Distributed Face Network in Adolescents with Autism
QuelleIn: Developmental Science, 19 (2016) 2, S.306-317 (12 Seiten)
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Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN1363-755X
DOI10.1111/desc.12305
SchlagwörterAutism; Neurological Impairments; Cognitive Processes; Brain Hemisphere Functions; Adolescents; Comparative Analysis; Diagnostic Tests; Familiarity; Animals; Human Body; Responses; Social Influences
AbstractMultiple hypotheses have been offered to explain the impaired face-processing behavior and the accompanying underlying disruptions in neural circuitry among individuals with autism. We explored the specificity of atypical face-processing activation and potential alterations to fusiform gyrus (FG) morphology as potential underlying mechanisms. Adolescents with high functioning autism (HFA) and age-matched typically developing (TD) adolescents were scanned with sMRI and fMRI as they observed human and animal faces. In spite of exhibiting comparable face recognition behavior, the HFA adolescents evinced hypo-activation throughout the face-processing system in response to unfamiliar human, but not animal, faces. They also exhibited greater activation in affective regions of the face-processing network in response to animal, but not human, faces. Importantly, this atypical pattern of activation in response to human faces was not related to atypical structural properties of the FG. This atypical neural response to human faces in autism may stem from abnormalities in the ability to represent the reward value of social (i.e. conspecific) stimuli. (As Provided).
AnmerkungenWiley-Blackwell. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8598; Fax: 781-388-8232; e-mail: cs-journals@wiley.com; Web site: http://www.wiley.com/WileyCDA
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2020/1/01
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