Atypical Pupillary Light Reflex and Heart Rate Variability in Children with Autism Spectrum Disorder

Autor/inn/en	Daluwatte, Chathuri; Miles, Judith H.; Christ, Shawn E.; Beversdorf, David Q.; Takahashi, T. Nicole; Yao, Gang
Titel	Atypical Pupillary Light Reflex and Heart Rate Variability in Children with Autism Spectrum Disorder
Quelle	In: Journal of Autism and Developmental Disorders, 43 (2013) 8, S.1910-1925 (16 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-012-1741-3
Schlagwörter	Children; Autism; Pervasive Developmental Disorders; Eye Movements; Metabolism; Age Differences; Correlation + Suchen Sie Ihr Suchwort? Child; Kind; Kinder; Autismus; Augenbewegung; Stoffwechsel; Age; Difference; Age difference; Altersunterschied; Korrelation
Abstract	We investigated pupillary light reflex (PLR) in 152 children with ASD, 116 typically developing (TD) children, and 36 children with non-ASD neurodevelopmental disorders (NDDs). Heart rate variability (HRV) was measured simultaneously to study potential impairments in the autonomic nervous system (ANS) associated with ASD. The results showed that the ASD group had significantly longer PLR latency, reduced relative constriction amplitude, and shorter constriction/redilation time than those of the TD group. Similar atypical PLR parameters were observed in the NDD group. A significant age effect on PLR latency was observed in children younger than 9 years in the TD group, but not in the ASD and NDD groups. Atypical HRV parameters were observed in the ASD and NDD groups. A significant negative correlation existed between the PLR constriction amplitude and average heart rate in children with an ASD, but not in children with typical development. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10