Literaturnachweis - Detailanzeige
Autor/inn/en | Barrette-Ng, Isabelle H.; Usher, Ken C. |
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Titel | A Novel Active-Learning Protein Purification Exercise for Large-Enrollment Introductory Biochemistry Courses Using the CHROM Web Applet |
Quelle | In: Journal of Chemical Education, 90 (2013) 2, S.252-253 (2 Seiten)Infoseite zur Zeitschrift
PDF als Volltext |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 0021-9584 |
DOI | 10.1021/ed300304d |
Schlagwörter | Biochemistry; Active Learning; Science Instruction; Introductory Courses; Computer Uses in Education; Problem Solving; Thinking Skills; Undergraduate Students; Instructional Effectiveness; Science Activities |
Abstract | The CHROM Web applet has been used to create a new active-learning exercise in which students design a purification scheme for a recombinant protein using ion-exchange chromatography (IEC). To successfully complete the exercise, students are challenged to apply elementary concepts from acid-base chemistry as well as protein and amino acid structure to devise a scheme purifying the target recombinant protein from other "Escherichia coli" proteins. By actively applying fundamental principles to solve an unfamiliar problem, students develop higher-level cognitive skills and gain a deeper understanding of key concepts that are difficult to teach effectively through traditional methods. The effectiveness of the exercise in promoting deep learning was assessed by comparing the performance of students in answering questions on acid-base chemistry, amino acid structure, and IEC before and after the completion of the active-learning exercise. (As Provided). |
Anmerkungen | Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2017/4/10 |