Exploring Machine Learning Techniques Using Patient Interactions in Online Health Forums to Classify Drug Safety

Autor/in	Chee, Brant Wah Kwong
Titel	Exploring Machine Learning Techniques Using Patient Interactions in Online Health Forums to Classify Drug Safety
Quelle	(2011), (194 Seiten) PDF als Volltext Verfügbarkeit Ph.D. Dissertation, University of Illinois at Urbana-Champaign
Sprache	englisch
Dokumenttyp	gedruckt; online; Monographie
ISBN	978-1-2672-6741-2
Schlagwörter	Hochschulschrift; Dissertation; Information Dissemination; Computer Mediated Communication; Natural Language Processing; Drug Use; Safety; Educational Technology; Pharmacology; Health Promotion; Health Education; Patient Education + Suchen Sie Ihr Suchwort? Thesis; Dissertations; Academic thesis; Informationsverbreitung; Computerkonferenz; Natürliche Sprache; Drug consumption; Substance abuse; Drogenkonsum; Sicherheit; Unterrichtsmedien; Arzneikunde; Gesundheitsfürsorge; Gesundheitshilfe; Reihenuntersuchung; Gesundheitsaufklärung; Gesundheitsbildung; Gesundheitserziehung
Abstract	This dissertation explores the use of personal health messages collected from online message forums to predict drug safety using natural language processing and machine learning techniques. Drug safety is defined as any drug with an active safety alert from the US Food and Drug Administration (FDA). It is believed that this is the first exploration of patient derived data of this type for pharmacovigilance--the study of drugs once released to market for safety. It is believed that this is the first application of machine learning and natural language processing techniques to be used for pharmicovigilance on patient derived data. We present results demonstrating the identification of drugs withdrawn from market as well as predictions of other potential safety alert drugs. One example includes Meridia, a weight loss drug linked with death for those with cardiovascular disease. The drug is identified based on data presented two years before FDA and European Union (EU) advisory panels were formed and the subsequent withdrawal of the drug from market within the EU and United States. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.] (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10