Heritability of objectively assessed and self-reported sedentary behavior.

Autor/inn/en	Schutte, Nienke M.; Huppertz, Charlotte; Doornweerd, Stieneke; Bartels, Meike; Geus, Eco J. C. de; Ploeg, Hidde P. van der
Titel	Heritability of objectively assessed and self-reported sedentary behavior. Gefälligkeitsübersetzung: Objektiv bewertete Heritabilität und selbst berichtetes sitzendes Verhalten.
Quelle	In: Scandinavian journal of medicine & science in sports, 30 (2020) 7, S. 1237-1247 PDF als Volltext Link als defekt meldenVerfügbarkeit
Sprache	englisch
Dokumenttyp	online; Zeitschriftenaufsatz
ISSN	0905-7188; 1600-0838
DOI	10.1111/sms.13658
Schlagwörter	Fragebogen; Korrelationsanalyse; Umwelteinfluss; Selbstbeobachtung; Gesundheitserziehung; Sportmedizin; Genetik; Selbstbeobachtung; Analyse; Zwillingsforschung; Fragebogen; Sitzen; Gesundheitsfürsorge; Korrelationsanalyse; Gesundheitsförderung; Genetik; Zwillingsforschung; Gesundheitserziehung; Gesundheitsförderung; Gesundheitsfürsorge; Sitzen; Sportmedizin; Analyse
Abstract	Understanding the sources of the large individual differences in sedentary behavior is of great importance as this behavior is associated with pre-mature mortality and non-communicable diseases. Here, we report on the contribution of genetic and environmental factors to the variation in objectively assessed (accelerometer) sedentary behavior and self-reported sitting and their shared genetic basis. In addition, the overlap of the genetic risk factors influencing sedentary time and moderate-to-vigorous physical activity (MVPA) was estimated. A sample of 800 individuals (twins and their siblings) was equipped with an Actigraph accelerometer for 7 days and reported on their sitting time and time spent on MVPA on those days using the IPAQ-SF. Genetic factors explained 56% (CI: 44%, 65%) of the individual differences in objective sedentary behavior (Actigraph) and 26% (CI: 0%, 51%) of the individual differences in self-reported sedentary behavior (IPAQ-SF). A modest correlation (0.33) was found between these measures, which was for 45% accounted for by genetic influences. The genetic correlation was 0.49 reflecting a partly overlapping set of genes that influenced both measurements. A modest correlation (-0.27) between Actigraph-derived sedentary time and MVPA was found, which was 13% accounted for by genetic effects. The genetic correlation was -0.31, indicating that there are overlapping genetic variants that increase sedentary time and decrease MVPA or vice versa. To conclude, more than half of the individual differences in objective sedentary time could be attributed to genetic differences, while for self-reported sitting this was much lower. In addition, using objective measurements, this study confirms that sedentary time is not simply the inverse of MVPA. Future studies are needed to understand the pathways translating genomic variation into variation in these behaviors and how this knowledge might feed into the development of health promotion interventions. (Autor).
Erfasst von	Bundesinstitut für Sportwissenschaft, Bonn
Update	2021/1