Protective effects of photobiomodulation against resistance exercise-induced muscle damage and inflammation in rats.

Autor/inn/en	Oliveira, Helenita Antonia de; Antonio, Ednei Luiz; Silva, Flávio André; Carvalho, Paulo de Tarso Camillo de; Feliciano, Regiane; Yoshizaki, Amanda; Vieira, Stella de Souza; Melo, Brunno Lemes de; Leal-Junior, Ernesto Cesar Pinto; Labat, Rodrigo; Bocalini, Danilo Sales; Silva Junior, José Antonio; Tucci, Paulo José Ferreira; Serra, Andrey Jorge
Titel	Protective effects of photobiomodulation against resistance exercise-induced muscle damage and inflammation in rats. Gefälligkeitsübersetzung: Schützende Effekte der Photobiomodulation gegen krafttrainingsinduzierte Muskelverletzung und Entzündungsmarker bei Ratten.
Quelle	In: Journal of sports sciences, 36 (2018) 20, S. 2349-2357 PDF als Volltext Link als defekt meldenVerfügbarkeit
Sprache	englisch
Dokumenttyp	online; gedruckt; Zeitschriftenaufsatz
ISSN	0264-0414; 1466-447X
DOI	10.1080/02640414.2018.1457419
Schlagwörter	Forschung; Vergleichsuntersuchung; Biologie; Entzündung; Forschung; Gesundheit; Gesundheitserziehung; Laser; Molekularbiologie; Tierversuch; Krafttraining; Analyse; Fotometrie; Biologie; Molekularbiologie; Tierversuch; Entzündung; Gesundheit; Gesundheitserziehung; Fotometrie; Laser; Krafttraining; Analyse
Abstract	We investigated whether low-level laser therapy (LLLT) prior to or post resistance exercise could attenuate muscle damage and inflammation. Female Wistar rats were assigned to non-LLLT or LLLT groups. An 830-nm DMC Laser Photon III was used to irradiate their hind legs with 2J, 4J, and 8J doses. Irradiations were performed prior to or post (4J) resistance exercise bouts. Resistance exercise consisted of four maximum load climbs. The load work during a resistance exercise bout was similar between Control (non-LLLT, 225 ± 10 g), 2J (215 ± 8 g), 4J (210 ± 9 g), and 8J (226 ± 9 g) groups. Prior LLLT did not induce climbing performance improvement, but exposure to 4J irradiation resulted in lower blood lactate levels post-exercise. The 4J dose decreased creatine kinase and lactic dehydrogenase levels post-exercise regardless of the time of application. Moreover, 4-J irradiation exposure significantly attenuated tumor necrosis factor alpha, interleukin-6, interleukin-1beta, cytokine-induced neutrophil chemoattractant-1, and monocyte chemoattractant protein-1. There was minor macrophage muscle infiltration in 4J-exposed rats. These data indicate that LLLT prior to or post resistance exercise can reduce muscle damage and inflammation, resulting in muscle recovery improvement. We attempted to determine an ideal LLLT dose for suitable results, wherein 4J irradiation exposure showed a significant protective role.
Erfasst von	Bundesinstitut für Sportwissenschaft, Bonn
Update	2019/2