Impaired and preserved aspects of independent finger control in patients with cerebellar damage.

Autor/inn/en	Brandauer, Barbara; Hermsdörfer, Joachim; Geißendörfer, Theresa; Schoch, Beate; Gizewski, Elke R.; Timmann, Dagmar
Titel	Impaired and preserved aspects of independent finger control in patients with cerebellar damage. Gefälligkeitsübersetzung: Geschädigte und unbeeinträchtigte Aspekte der unabhängigen Fingerkontrolle bei Patienten mit Kleinhirnschädigungen.
Quelle	In: Journal of neurophysiology, 107 (2012) 4, S. 1080-1093 PDF als Volltext kostenfreie Datei Link als defekt meldenVerfügbarkeit
Sprache	englisch
Dokumenttyp	online; gedruckt; Zeitschriftenaufsatz
ISSN	0022-3077; 1522-1598
DOI	10.1152/jn.00142.2011
Schlagwörter	Motorik; Psychomotorik; Bewegungskontrolle; Hand; Motorik; Neurologie; Neurophysiologie; Psychomotorik; Bewegungsstörung; Bewegungsanalyse; Kleinhirn; Finger; Finger; Hand; Kleinhirn; Bewegung (Motorische); Bewegungsanalyse; Sensumotorik; Neurologie; Neurophysiologie; Bewegungsstörung
Abstract	The influence of the cerebellum on independent finger control has rarely been investigated. We examined multidigit control in 22 patients with cerebellar degeneration, 20 patients with cerebellar stroke, and 21 patients with surgical lesions after cerebellar tumor removal. In the first task, either the index finger or the middle finger was actively lifted from an object during static holding. Both controls and cerebellar patients increased the forces of the nearby digits in synchrony with lift-off to maintain the total finger force. Patients used increased finger forces but showed no significant deficits in the pattern and timing of rearrangement of finger forces. In the second task, subjects had to press and release one finger against a force-sensitive keypad with the other fingers being inactive. All patient groups showed increased force production of the noninstructed (enslaved) fingers compared with controls. Lesion-symptom mapping in the focal patients revealed that lesions of the superior hand area were related to abnormal levels of enslaving. Increased finger forces in the finger-lifting task likely reflect an unspecific safety strategy. Increased effects of enslaving in the individuated key-press task, however, may be explained by a deterioration of cerebellar contribution to feedforward commands necessary to suppress activity in noninstructed fingers or by increased spread of the motor command intended for the instructed finger. Despite the large and diverse patient sample, surprisingly few abnormalities were observed. Both holding an object and finger typing are overlearned, automatized motor tasks, which may not or little depend on the integrity of the cerebellum. Verf.-Referat.
Erfasst von	Bundesinstitut für Sportwissenschaft, Bonn
Update	2015/1