Practitioner Review: Use of Antiepileptic Drugs in Children

Autor/inn/en	Guerrini, Renzo; Parmeggiani, Lucio
Titel	Practitioner Review: Use of Antiepileptic Drugs in Children
Quelle	In: Journal of Child Psychology and Psychiatry, 47 (2006) 2, S.115-126 (12 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9630
DOI	10.1111/j.1469-7610.2005.01458.x
Schlagwörter	Epilepsy; Narcotics; Seizures; Identification; Pathology; Clinical Experience; Children; Drug Therapy; Drug Use; Outcomes of Treatment; Clinical Diagnosis; Medicine; Behavior; Psychomotor Skills + Suchen Sie Ihr Suchwort? Epilepsie; Narcotic; Betäubungsmittel; Anfallsleiden; Identifikation; Identifizierung; Pathologie; Child; Kind; Kinder; Drug consumption; Substance abuse; Drogenkonsum; Medizin; Psychomotorische Aktivität
Abstract	Background: The aim in treating epilepsy is to minimise or control seizures with full respect of quality-of-life issues, especially of cognitive functions. Optimal treatment first demands a correct recognition of the major type of seizures, followed by a correct diagnosis of the type of epilepsy or of the specific syndrome. Methods: Review of data from literature and personal clinical experience in treating children with epilepsy. Results: After summarising the general aspects on the diagnosis and treatment of the main forms of childhood epilepsy, we review key issues about management of seizure disorders, including when to start treatment, how to proceed when the first treatment fails, and how to set the targets of treatment. A special section is devoted to the new concept of epileptic encephalopathy and to the influence of "interictal" EEG abnormalities on cognition, behaviour, and motor abilities in children, providing some suggestions on why and how to treat these conditions. A second section approaches the choice of treatment according to the specific syndromes including infantile spasms, focal epilepsies, syndromes with typical absence seizures, the myoclonic epilepsies and the Lennox-Gastaut syndrome. Conclusions: Antiepileptic drugs (AEDs) can efficiently control seizures in most children. However, the specificity of AEDs is relatively limited, although continuing research is leading to a better understanding of the relationship between pathogenesis and the mechanism(s) and site(s) of drug action. (As Provided).
Anmerkungen	Wiley-Blackwell. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8598; Fax: 781-388-8232; e-mail: cs-journals@wiley.com; Web site: http://www.wiley.com/WileyCDA/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10