Gene-Environment Interplay between Peer Rejection and Depressive Behavior in Children

Autor/inn/en	Brendgen, Mara; Vitaro, Frank; Boivin, Michel; Girard, Alain; Bukowski, William M.; Dionne, Ginette; Tremblay, Richard E.; Perusse, Daniel
Titel	Gene-Environment Interplay between Peer Rejection and Depressive Behavior in Children
Quelle	In: Journal of Child Psychology and Psychiatry, 50 (2009) 8, S.1009-1017 (9 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9630
DOI	10.1111/j.1469-7610.2009.02052.x
Schlagwörter	Twins; Peer Groups; Genetics; Peer Acceptance; Rejection (Psychology); Depression (Psychology); Children; Risk; Environmental Influences; Kindergarten; Measurement; Role + Suchen Sie Ihr Suchwort? Twin; Zwilling; Gleichaltrigengruppe; Peer Group; Humangenetik; Ablehnung; Child; Kind; Kinder; Risiko; Environmental influence; Umwelteinfluss; Messverfahren; Rollen
Abstract	Background: Genetic risk for depressive behavior may increase the likelihood of exposure to environmental stressors (gene-environment correlation, rGE). By the same token, exposure to environmental stressors may moderate the effect of genes on depressive behavior (gene-environment interaction, GxE). Relating these processes to a peer-related stressor in childhood, the present study examined (1) whether genetic risk for depressive behavior in children is related to higher levels of rejection by the peer group (rGE) and (2) whether peer rejection moderates the effect of genetic factors on children's depressive behavior (GxE). Methods: The sample comprised 336 twin pairs (MZ pairs = 196, same-sex DZ pairs = 140) assessed in kindergarten (mean age 72.7 months). Peer acceptance/rejection was measured via peer nominations. Depressive behavior was measured through teacher ratings. Results: Consistent with rGE, a moderate overlap of genetic effects was found between peer acceptance/rejection and depressive behavior. In line with GxE, genetic effects on depressive behavior varied across levels of peer acceptance/rejection. Conclusions: An increased genetic disposition for depressive behavior is related to a higher risk of peer rejection (rGE). However, genes play a lesser role in explaining individual differences in depressive behavior in rejected children than in accepted children (GxE). (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10