Multidimensional Sequence Learning in Patients with Focal Basal Ganglia Lesions

Autor/inn/en	Shin, J.C.; Aparicio, P.; Ivry, R.B.
Titel	Multidimensional Sequence Learning in Patients with Focal Basal Ganglia Lesions
Quelle	In: Brain and Cognition, 58 (2005) 1, S.75-83 (9 Seiten) PDF als Volltext Verfügbarkeit
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0278-2626
DOI	10.1016/j.bandc.2004.09.015
Schlagwörter	Patients; Methods; Intervals; Reaction Time + Suchen Sie Ihr Suchwort? Patient; Method; Methode; Reaktionsvermögen
Abstract	Parkinson's patients have been found to be impaired in learning movement sequences. In the current study, patients with unilateral basal ganglia lesions due to stroke were tested on a serial reaction time task in which responses were based on the spatial location of each stimulus. The spatial locations either followed a fixed sequence or were selected at random, with learning operationalized as the difference in reaction time between these two conditions. In addition, three response-to-stimulus intervals were used, and these either followed a fixed sequence or were randomized. Compared to control participants, the patients showed normal learning of the spatial and temporal sequences, as well as normal cross-dimensional learning. This was true for performance with either the contralesional or ipsilesional hand. Sequence learning was not correlated with maximum tapping rate, a simple measure of motor impairment. These results raise questions concerning the use of Parkinson's disease as a model for studying basal ganglia dysfunction. (Author).
Anmerkungen	Elsevier Customer Service Department, 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126 (Toll Free); Fax: 407-363-1354; e-mail: usjcs@elsevier.com.
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10