Neural Changes after Phonological Treatment for Anomia: An fMRI Study

Autor/inn/en	Rochon, Elizabeth; Leonard, Carol; Burianova, Hana; Laird, Laura; Soros, Peter; Graham, Simon; Grady, Cheryl
Titel	Neural Changes after Phonological Treatment for Anomia: An fMRI Study
Quelle	In: Brain and Language, 114 (2010) 3, S.164-179 (16 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0093-934X
DOI	10.1016/j.bandl.2010.05.005
Schlagwörter	Control Groups; Brain Hemisphere Functions; Phonology; Semantics; Aphasia; Patients; Semiotics; Disabilities; Outcomes of Treatment; Cognitive Processes; Neurological Impairments + Suchen Sie Ihr Suchwort? Fonologie; Semantik; Expressive Aphasie; Aphasie; Patient; Semiotik; Handicap; Behinderung; Cognitive process; Kognitiver Prozess; Neurodegenerative Erkrankung
Abstract	Functional magnetic resonance imaging (fMRI) was used to investigate the neural processing characteristics associated with word retrieval abilities after a phonologically-based treatment for anomia in two stroke patients with aphasia. Neural activity associated with a phonological and a semantic task was compared before and after treatment with fMRI. In addition to the two patients who received treatment, two patients with aphasia who did not receive treatment and 10 healthy controls were also scanned twice. In the two patients who received treatment, both of whose naming improved after treatment, results showed that activation patterns changed after treatment on the semantic task in areas that would have been expected (e.g., left hemisphere frontal and temporal areas). For one control patient, there were no significant changes in brain activation at the second scan; a second control patient showed changes in brain activation at the second scan, on the semantic task, however, these changes were not accompanied with improved performance in naming. In addition, there appeared to be bilateral, or even more right than left hemisphere brain areas activated in this patient than in the treated patients. The healthy control group showed no changes in activation at the second scan. These findings are discussed with reference to the literature on the neural underpinnings of recovery after treatment for anomia in aphasia. (Contains 5 tables and 7 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10