The Prodrome of Autism: Early Behavioral and Biological Signs, Regression, Peri- and Post-Natal Development and Genetics

Autor/inn/en	Yirmiya, Nurit; Charman, Tony
Titel	The Prodrome of Autism: Early Behavioral and Biological Signs, Regression, Peri- and Post-Natal Development and Genetics
Quelle	In: Journal of Child Psychology and Psychiatry, 51 (2010) 4, S.432-458 (27 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9630
DOI	10.1111/j.1469-7610.2010.02214.x
Schlagwörter	Symptoms (Individual Disorders); Autism; Infants; Genetics; Classification; Identification; Coding; Video Technology; At Risk Persons; Siblings; Evaluation Criteria; Brain; Prenatal Influences; Prevention; Developmental Stages; South Africa + Suchen Sie Ihr Suchwort? Psychiatrische Symptomatik; Autismus; Infant; Toddler; Toddlers; Kleinkind; Humangenetik; Classification system; Klassifikation; Klassifikationssystem; Identifikation; Identifizierung; Codierung; Programmierung; Risikogruppe; Sibling; Geschwister; Gehirn; Pränataler Einfluss; Prävention; Vorbeugung; Südafrika; Süd-Afrika; Republik Südafrika; Südafrikanische Republik
Abstract	Autism is one of the most heritable neurodevelopmental conditions and has an early onset, with symptoms being required to be present in the first 3 years of life in order to meet criteria for the "core" disorder in the classification systems. As such, the focus on identifying a prodrome over the past 20 years has been on pre-clinical signs or indicators that will be present very early in life, certainly in infancy. A number of novel lines of investigation have been used to this end, including retrospective coding of home videos, prospective population screening and "high risk" sibling studies; as well as the investigation of pre- and peri-natal, brain developmental and other biological factors. While no single prodromal sign is expected to be present in all cases, a picture is emerging of indicative prodromal signs in infancy and initial studies are being undertaken to attempt to ameliorate early presentation and even "prevent" emergence of the full syndrome. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10