Double Dissociation of Pharmacologically Induced Deficits in Visual Recognition and Visual Discrimination Learning

Autor/inn/en	Turchi, Janita; Buffalari, Deanne; Mishkin, Mortimer
Titel	Double Dissociation of Pharmacologically Induced Deficits in Visual Recognition and Visual Discrimination Learning
Quelle	In: Learning & Memory, 15 (2008) 8, S.565-568 (4 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.966208
Schlagwörter	Habit Formation; Intervals; Discrimination Learning; Visual Discrimination; Recognition (Psychology); Drug Therapy; Learning Processes; Neuropsychology; Retention (Psychology); Primatology + Suchen Sie Ihr Suchwort? Lernen; Lernprozess; Recognition; Wiedererkennen; Learning process; Neuropsychologie; Merkfähigkeit
Abstract	Monkeys trained in either one-trial recognition at 8- to 10-min delays or multi-trial discrimination habits with 24-h intertrial intervals received systemic cholinergic and dopaminergic antagonists, scopolamine and haloperidol, respectively, in separate sessions. Recognition memory was impaired markedly by scopolamine but not at all by haloperidol, whereas habit formation was impaired markedly by haloperidol but only minimally by scopolamine. These differential drug effects point to differences in synaptic modification induced by the two neuromodulators that parallel the contrasting properties of the two types of learning, namely, fast acquisition but weak retention of memories versus slow acquisition but durable retention of habits. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10