Daily Access to Sucrose Impairs Aspects of Spatial Memory Tasks Reliant on Pattern Separation and Neural Proliferation in Rats

Autor/inn/en	Reichelt, Amy C.; Morris, Margaret J.; Westbrook, Reginald Frederick
Titel	Daily Access to Sucrose Impairs Aspects of Spatial Memory Tasks Reliant on Pattern Separation and Neural Proliferation in Rats
Quelle	In: Learning & Memory, 23 (2016) 7, S.386-390 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.042416.116
Schlagwörter	Animals; Spatial Ability; Control Groups; Memory; Dietetics; Visual Discrimination; Biochemistry; Brain Hemisphere Functions; Interference (Learning); Task Analysis; Novelty (Stimulus Dimension) + Suchen Sie Ihr Suchwort? Animal; Tier; Tiere; Räumliches Vorstellungsvermögen; Gedächtnis; Ernährungslehre; Biochemie; Aufgabenanalyse
Abstract	High sugar diets reduce hippocampal neurogenesis, which is required for minimizing interference between memories, a process that involves "pattern separation." We provided rats with 2 h daily access to a sucrose solution for 28 d and assessed their performance on a spatial memory task. Sucrose consuming rats discriminated between objects in novel and familiar locations when there was a large spatial separation between the objects, but not when the separation was smaller. Neuroproliferation markers in the dentate gyrus of the sucrose-consuming rats were reduced relative to controls. Thus, sucrose consumption impaired aspects of spatial memory and reduced hippocampal neuroproliferation. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01