Rapid Association Learning in the Primate Prefrontal Cortex in the Absence of Behavioral Reversals

Autor/inn/en	Cromer, Jason A.; Machon, Michelle; Miller, Earl K.
Titel	Rapid Association Learning in the Primate Prefrontal Cortex in the Absence of Behavioral Reversals
Quelle	In: Journal of Cognitive Neuroscience, 23 (2011) 7, S.1823-1828 (6 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0898-929X
DOI	10.1162/jocn.2010.21555
Schlagwörter	Stimuli; Prior Learning; Brain Hemisphere Functions; Animals; Role; Learning Processes; Associative Learning; Cues; Conditioning; Primatology + Suchen Sie Ihr Suchwort? Anreizsystem; Vorkenntnisse; Animal; Tier; Tiere; Rollen; Learning process; Lernprozess; Stichwort
Abstract	The PFC plays a central role in our ability to learn arbitrary rules, such as "green means go." Previous experiments from our laboratory have used conditional association learning to show that slow, gradual changes in PFC neural activity mirror monkeys' slow acquisition of associations. These previous experiments required monkeys to repeatedly reverse the cue-saccade associations, an ability known to be PFC-dependent. We aimed to test whether the relationship between PFC neural activity and behavior was due to the reversal requirement, so monkeys were trained to learn several new conditional cue-saccade associations without reversing them. Learning-related changes in PFC activity now appeared earlier and more suddenly in correspondence with similar changes in behavioral improvement. This suggests that learning of conditional associations is linked to PFC activity regardless of whether reversals are required. However, when previous learning does not need to be suppressed, PFC acquires associations more rapidly. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10