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Autor/inn/enBrunamonti, Emiliano; Pani, Pierpaolo; Papazachariadis, Odysseas; Onorati, Paolo; Albertini, Giorgio; Ferraina, Stefano
TitelCognitive Control of Movement in Down Syndrome
QuelleIn: Research in Developmental Disabilities: A Multidisciplinary Journal, 32 (2011) 5, S.1792-1797 (6 Seiten)Infoseite zur Zeitschrift
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Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN0891-4222
DOI10.1016/j.ridd.2011.03.008
SchlagwörterMental Age; Reaction Time; Down Syndrome; Inhibition; Patients; Etiology; Cognitive Processes; Motion; Investigations; Brain; Adults; Developmental Disabilities; Cognitive Development
AbstractInhibition of inappropriate responses allows to shape the motor behavior accordingly to the context in which a subject acts and is an essential executive function. Inhibition has been poorly investigated in Down Syndrome (DS) patients. We tested, using a countermanding task, the inhibitory control in a group of DS patients and in a group of patients with developmental disorders of non-genetic etiology, matched for mental age. We found that the duration of the stopping process, the stop signal reaction time (SSRT), was not statistically different in the two groups of patients. At the same time, the normalized inhibitory function resulted shallower in DS patients indicating a poor inhibitory control. We interpreted the results on the basis of the known anatomical differences in the brain of adult DS patients and more specifically in a possible altered dialogue between the fronto-striatal and fronto-cerebellar networks during motor control. (Contains 3 figures.) (As Provided).
AnmerkungenElsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2017/4/10
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